rs4759229

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

adult onset asthma, body mass index

Zhu Z et al. “Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.” The Journal of Allergy and Clinical Immunology 145(2):537-549 (2020)

Allele A

OR —

p 2.0e-23

N 457,822

Major Consortium StudyLarge GWAS

European

asthma, body mass index

Zhu Z et al. “Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.” The Journal of Allergy and Clinical Immunology 145(2):537-549 (2020)

Allele A

OR —

p 2.0e-21

N 457,822

Major Consortium StudyLarge GWAS

European

smoking status measurement

Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)

Allele G

OR 0.02

p 7.0e-9

N 1,232,091

Large GWAS

European

cortical thickness

Shadrin AA et al. “Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.” Neuroimage 244:118603 (2021)

Allele A

OR —

p 4.0e-8

N 35,657

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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