rs4778734

This is a regulatory region variant variant in the ST20 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

eosinophil count

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele G

OR 0.02

p 5.0e-30

N 442,919

Large GWAS

multi-ancestry

About ST20

Enables cysteine-type endopeptidase activator activity. Involved in apoptotic signaling pathway and cellular response to UV-C. [provided by Alliance of Genome Resources, Jul 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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