rs4789229

This variant is located in the UNK gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

apolipoprotein A 1 measurement, apolipoprotein B measurement

Karjalainen MK et al. “Genome-wide characterization of circulating metabolic biomarkers.” Nature 628(8006):130-138 (2024)

Allele T

OR 0.03

p 2.0e-12

N 136,016

Large GWAS

multi-ancestry

phospholipids:total lipids ratio

Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)

Allele T

OR 0.01

p 3.0e-12

N 450,015

Large GWAS

multi-ancestry

About UNK

Enables mRNA CDS binding activity. Involved in cell morphogenesis involved in neuron differentiation and negative regulation of cytoplasmic translation. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all UNK variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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