rs4814861

This variant is located in the SLC24A3 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

migraine disorder

Allele A
OR 1.06
p 1.0e-22
N 889,018
Meta-analysisLarge GWAS
European

About SLC24A3

Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]

View all SLC24A3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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