rs4814873
This is a intron variant variant in the SLC24A3 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
smoking behavior trait
Wootton RE et al. “Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study.” Psychological Medicine 50(14):2435-2443 (2020)
Allele C
OR 0.01
p 3.0e-9
N 462,690
Large GWAS
European
About SLC24A3
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]
View all SLC24A3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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