rs4850954

▶

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

aspartate aminotransferase to alanine aminotransferase ratio

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele T

OR 0.03

p 3.0e-25

N 389,315

Major Consortium StudyLarge GWAS

European

educational attainment

Okbay A et al. “Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.” Nature Genetics 54(4):437-449 (2022)

Allele T

OR 0.01

p 7.0e-15

N 3,037,499

Large GWAS

European

posterior thigh muscle fat infiltration measurement

van der Meer D et al. “The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition.” Communications Biology 5(1):1271 (2022)

Allele T

OR 5.96

p 2.0e-9

N 32,956

Large GWAS

European

self reported educational attainment

Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)

Allele T

OR 0.01

p 4.0e-8

N 1,131,881

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…