rs4903064

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GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

renal carcinoma

Purdue MP et al. “Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions.” Nature Genetics 56(5):809-818 (2024)
Allele C
OR 1.22
p 2.0e-59
N 864,690
Large GWAS
multi-ancestry

clear cell renal carcinoma

Purdue MP et al. “Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions.” Nature Genetics 56(5):809-818 (2024)
Allele C
OR 1.27
p 9.0e-54
N 759,800
Large GWAS
multi-ancestry

retinal layer thickness

Jackson VE et al. “Multi-omic spatial effects on high-resolution AI-derived retinal thickness.” Nature Communications 16(1):1317 (2025)
Allele C
OR 0.50
p 2.0e-27
N 43,148
Large GWAS
multi-ancestry

renal cell carcinoma

Scelo G et al. “Genome-wide association study identifies multiple risk loci for renal cell carcinoma.” Nature Communications 8:15724 (2017)
Allele C
OR 1.21
p 2.0e-24
N 31,190
Large GWAS
European
Laskar RS et al. “Sex specific associations in genome wide association analysis of renal cell carcinoma.” European Journal of Human Genetics : Ejhg 27(10):1589-1598 (2019)
Allele C
OR 1.38
p 2.0e-14
N 5,087
Large GWAS
European

pulse pressure measurement

Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)
Allele C
OR 0.17
p 6.0e-17
N 1,028,980
Large GWAS
multi-ancestry

diastolic blood pressure

Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)
Allele C
OR 0.15
p 2.0e-16
N 1,028,980
Large GWAS
multi-ancestry
Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)
Allele C
OR 0.01
p 6.0e-12
N 1,212,859
Large GWAS
European
Plotnikov D et al. “High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study.” Investigative Ophthalmology & Visual Science 63(6):29 (2022)
Allele C
OR 0.16
p 1.0e-10
N 526,001
Large GWAS
European

photoreceptor cell layer thickness measurement

Nakao SY et al. “A genome-wide association between foveal thickness and arrhythmia.” Communications Medicine 5(1):374 (2025)
Allele T
OR 2.18
p 3.0e-13
N 3,451
Large GWAS
East Asian

diastolic blood pressure change measurement

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.02
p 3.0e-12
N 609,486
Major Consortium StudyLarge GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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