rs4908185
This is a intron variant variant in the OLFM3 gene.
▶Research that mentions this SNP (1)
▶Genome-wide genotype-based risk model for survival in core binding factor acute myeloid leukemia patientsAssociationN=104Silvia Park et al.(2018)· Annals of Hematology
This genome-wide SNP association study in 104 core binding factor acute myeloid leukemia (CBF-AML) patients developed predictive risk models for overall survival (OS) and event-free survival (EFS) incorporating six SNPs each combined with clinical factors. The OS model significantly stratified patients into low- and high-risk groups with 3-year survival rates of 80.4% vs 22.0% (p=8.75×10⁻¹³), while the EFS model achieved 75.0% vs 17.1% (p=5.95×10⁻¹³), demonstrating that genome-wide SNP genotyping can improve survival prediction in CBF-AML beyond conventional clinical factors.
About OLFM3
Predicted to be involved in signal transduction. Predicted to be located in Golgi apparatus; extracellular region; and synapse. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]
View all OLFM3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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