rs4921484
This variant is located in the LOC285626 gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of interleukin-12 subunit beta in blood
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele T
OR 0.51
p 2.0e-162
N 5,363
Large GWAS
European
blood protein amount
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele T
OR 0.42
p 3.0e-105
N 5,368
Large GWAS
European
interleukin-23 measurement
Thareja G et al. “Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations.” Human Molecular Genetics 32(6):907-916 (2023)
Allele T
OR 0.48
p 2.0e-61
N 2,935
Large GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
Allele T
OR 0.31
p 7.0e-33
N 3,301
Large GWAS
European
Oral ulcer
Dudding T et al. “Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci.” Nature Communications 10(1):1052 (2019)
Allele C
OR 1.05
p 1.0e-28
N 461,106
Large GWAS
European, NR
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…