rs4921914
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (20)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (20)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
5-acetylamino-6-formylamino-3-methyluracil measurement
Hysi PG et al. “Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.” Metabolites 12(1) (2022)
Allele C
OR 0.87
p —
N 8,809
Large GWAS
European
N-acetylputrescine measurement
Hysi PG et al. “Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.” Metabolites 12(1) (2022)
Allele C
OR 0.54
p 2.0e-206
N 8,809
Large GWAS
European
5-acetylamino-6-amino-3-methyluracil measurement
Hysi PG et al. “Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.” Metabolites 12(1) (2022)
Allele C
OR 0.45
p 4.0e-143
N 8,809
Large GWAS
European
1-methylxanthine measurement
Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele T
OR 0.09
p 1.0e-60
N 5,504
Large GWAS
European
4-acetamidobutanoate measurement
Schlosser P et al. “Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.” Nature Genetics 55(6):995-1008 (2023)
Allele T
OR 0.17
p 5.0e-59
N 4,910
Large GWAS
European
X-12410 measurement
Schlosser P et al. “Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.” Nature Genetics 55(6):995-1008 (2023)
Allele T
OR 0.33
p 2.0e-42
N 4,911
Large GWAS
European
urinary metabolite measurement
Rueedi R et al. “Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.” Plos Genetics 10(2):e1004132 (2014)
Allele T
OR 0.51
p 4.0e-32
N 835
Small GWAS
multi-ancestry
Schlosser P et al. “Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans.” Nature Genetics 52(2):167-176 (2020)
Allele T
OR 0.41
p 1.0e-11
N 1,221
Large GWAS
metabolite measurement
Suhre K et al. “A genome-wide association study of metabolic traits in human urine.” Nature Genetics 43(6):565-9 (2011)
Allele C
OR —
p 1.0e-28
N 862
Small GWAS
European
level of contactin-3 in blood serum
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.06
p 2.0e-26
N 47,745
Large GWAS
European
tyrosine measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 4.0e-24
N 450,015
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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