rs4923542

This is a intron variant variant in the METTL15 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

type 2 diabetes mellitus

Suzuki K et al. “Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.” Nature 627(8003):347-357 (2024)

Allele G

OR —

p 4.0e-13

N 2,535,601

Large GWAS

multi-ancestry

About METTL15

Enables rRNA (cytosine-N4-)-methyltransferase activity. Involved in rRNA base methylation. Is active in mitochondrial matrix. [provided by Alliance of Genome Resources, Jul 2025]

View all METTL15 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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