rs4938490

This variant is located in the JAML gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

blood protein amount

Emilsson V et al. Co-regulatory networks of human serum proteins link genetics to disease. Science (new York, N.y.) 361(6404):769-773 (2018)
Allele G
OR 0.87
p
N 3,200
Large GWAS
European

About JAML

Enables integrin binding activity and protein homodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and myeloid leukocyte migration. Located in bicellular tight junction; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all JAML variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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