rs4949874

This is a intergenic variant variant in the SLC44A5 gene.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

acetylcarnitine-to-hexanoylcarnitine ratio

Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)

Allele T

OR —

β 0.073

p 2.0e-172

N 5,568

Large GWAS

European

serum metabolite level

Feofanova EV et al. “A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos.” American Journal of Human Genetics 107(5):849-863 (2020)

Allele T

OR 0.36

p 9.0e-48

N 3,926

Large GWAS

Hispanic or Latin American

decanoylcarnitine measurement

Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)

Allele C

OR 0.31

p 1.0e-47

N 6,136

Large GWAS

European

About SLC44A5

Enables choline transmembrane transporter activity. Involved in choline transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all SLC44A5 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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