rs506589
This is a regulatory region variant variant.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
obese body mass index status
Riveros-McKay F et al. “Genetic architecture of human thinness compared to severe obesity.” Plos Genetics 15(1):e1007603 (2019)
Allele C
OR 1.28
p 3.0e-20
N 2,927
Large GWAS
European
smoking initiation
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele C
OR 0.01
p 6.0e-17
N 3,382,012
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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