rs527725

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

occlusion precerebral artery

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.08
p 9.0e-19
N 428,999
Major Consortium StudyLarge GWAS
European

pulse pressure measurement

Allele C
OR 0.20
p 3.0e-14
N 459,777
Large GWAS
multi-ancestry

aortic measurement

Allele A
OR 3.21
p 6.0e-9
N 32,590
Large GWAS
European

descending aorta diameter

Pirruccello JP et al. Deep learning enables genetic analysis of the human thoracic aorta. Nature Genetics 54(1):40-51 (2022)
Allele A
OR 0.04
p 6.0e-11
N 34,532
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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