rs528685139

This variant is located in the HTR1F gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Furuncle, carbuncle

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 1.74
p 2.0e-11
N 615,135
Major Consortium StudyLarge GWAS
multi-ancestry

About HTR1F

Enables Gi/o-coupled serotonin receptor activity; serotonin binding activity; and serotonin receptor activity. Involved in adenylate cyclase-inhibiting serotonin receptor signaling pathway. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all HTR1F variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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