rs529541
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
protein measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele A
OR 0.74
p —
N 10,708
Large GWAS
European
complement factor H-related protein 3 measurement
Suhre K et al. “A genome-wide association study of mass spectrometry proteomics using a nanoparticle enrichment platform.” Nature Genetics 57(12):2987-2996 (2025)
Allele G
OR 0.89
p 4.0e-126
N 1,247
Large GWAS
multi-ancestry
Lorés-Motta L et al. “Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR concentrations and age-related macular degeneration.” American Journal of Human Genetics 108(8):1367-1384 (2021)
Allele G
OR 1.16
p 2.0e-47
N 416
Small GWAS
European
rho guanine nucleotide exchange factor 10 measurement
Allele G
OR 0.31
p 7.0e-23
N 3,301
Large GWAS
European
interleukin-18 receptor 1 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.03
p 4.0e-17
N 47,745
Large GWAS
European
total blood protein measurement
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele G
OR 0.02
p 8.0e-15
N 448,242
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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