rs531877822

This variant is located in the NKAIN2 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

benign neoplasm of adrenal gland

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 2.93
p 2.0e-11
N 630,183
Major Consortium StudyLarge GWAS
multi-ancestry

About NKAIN2

This gene encodes a transmembrane protein that interacts with the beta subunit of a sodium/potassium-transporting ATPase. A chromosomal translocation involving this gene is a cause of lymphoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

View all NKAIN2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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