rs538628
This variant is located in the NSF gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
alopecia
Hagenaars SP et al. “Genetic prediction of male pattern baldness.” Plos Genetics 13(2):e1006594 (2017)
Allele C
OR —
β 0.080
p 4.0e-27
N 52,874
Large GWAS
European
educational attainment, alcohol use disorder measurement
Chen D et al. “Unraveling shared susceptibility loci and Mendelian genetic associations linking educational attainment with multiple neuropsychiatric disorders.” Frontiers in Psychiatry 14:1303430 (2023)
Allele C
OR —
p 4.0e-14
N 415,327
Large GWAS
European
feeling nervous measurement
Nagel M et al. “Item-level analyses reveal genetic heterogeneity in neuroticism.” Nature Communications 9(1):905 (2018)
Allele C
OR 7.14
p 9.0e-13
N 373,121
Large GWAS
European
About NSF
Enables PDZ domain binding activity and ionotropic glutamate receptor binding activity. Involved in intracellular protein transport; positive regulation of protein catabolic process; and positive regulation of receptor recycling. Located in Golgi apparatus; cytosol; and plasma membrane. Implicated in developmental and epileptic encephalopathy 96. [provided by Alliance of Genome Resources, Jul 2025]
View all NSF variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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