rs542077701

This variant is located in the DNER gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

knee fracture

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 3.27
p 3.0e-12
N 631,782
Major Consortium StudyLarge GWAS
multi-ancestry

About DNER

Predicted to enable Notch binding activity. Involved in central nervous system development. Located in dendrite; early endosome; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all DNER variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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