rs542275
This is a 3 prime utr variant variant in the LAYN gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
protein measurement
Western D et al. “Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.” Nature Genetics 56(12):2672-2684 (2024)
Allele C
OR 0.54
p 2.0e-133
N 3,506
Large GWAS
European
About LAYN
Enables hyaluronic acid binding activity. Located in focal adhesion. [provided by Alliance of Genome Resources, Jul 2025]
View all LAYN variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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