rs543863390

This variant is located in the TRHDE gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

esophageal ulcer

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 3.19
p 5.0e-12
N 628,505
Major Consortium StudyLarge GWAS
multi-ancestry

About TRHDE

This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.[provided by RefSeq, Dec 2008]

View all TRHDE variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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