rs545652970

This variant is located in the ADRB1 gene.

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ClinVar annotation

Likely Benign

1 submitter

ADRB1-related disorder

About ADRB1

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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