rs547300358

This variant is located in the DTWD2 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

male reproductive organ cancer

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 3.61
p 5.0e-12
N 520,899
Major Consortium StudyLarge GWAS
multi-ancestry

About DTWD2

Enables tRNA-uridine aminocarboxypropyltransferase activity. Involved in RNA glycosylation and tRNA modification. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all DTWD2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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