rs548227718
This variant is located in the FAF2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
chronic musculoskeletal pain
Tsepilov YA et al. “Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions.” Communications Biology 3(1):329 (2020)
Allele A
OR 0.28
p 3.0e-9
N 265,000
Large GWAS
multi-ancestry
About FAF2
The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008]
View all FAF2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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