rs548630

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)

Allele C

OR 0.02

p 2.0e-14

N 450,015

Large GWAS

multi-ancestry

von Willebrand factor quality

Sabater-Lleal M et al. “Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.” Circulation 139(5):620-635 (2019)

Allele A

OR 0.02

p 1.0e-12

N 46,354

Large GWAS

multi-ancestry

factor VIII measurement

Sabater-Lleal M et al. “Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.” Circulation 139(5):620-635 (2019)

Allele A

OR 0.02

p 5.0e-10

N 32,610

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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