rs549323446

This variant is located in the NCKAP5 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

tricuspid valve disease

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 3.12
p 4.0e-12
N 565,381
Major Consortium StudyLarge GWAS
multi-ancestry

About NCKAP5

Predicted to be involved in microtubule bundle formation and microtubule depolymerization. Predicted to be active in microtubule plus-end. [provided by Alliance of Genome Resources, Jul 2025]

View all NCKAP5 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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