rs553399706
This variant is located in the GLG1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Varicose veins
Fukaya E et al. “Clinical and Genetic Determinants of Varicose Veins.” Circulation 138(25):2869-2880 (2018)
Allele A
OR 1.06
p 1.0e-8
N 337,536
CohortLarge GWAS
European
About GLG1
Predicted to enable fibroblast growth factor binding activity. Predicted to act upstream of or within several processes, including negative regulation of protein processing; negative regulation of transforming growth factor beta receptor signaling pathway; and regulation of chondrocyte differentiation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]
View all GLG1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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