rs554894200

This is a intron variant variant in the NUP160 gene.

▶

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brain attribute

Bahrami S et al. “The genetic landscape of basal ganglia and implications for common brain disorders.” Nature Communications 15(1):8476 (2024)

Allele T

OR —

p 4.0e-10

N 34,794

Large GWAS

European

diastolic blood pressure change measurement

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)

Allele A

OR 0.03

p 2.0e-13

N 609,486

Major Consortium StudyLarge GWAS

multi-ancestry

About NUP160

A structural constituent of nuclear pore. Involved in mRNA export from nucleus and nephron development. Located in kinetochore and nuclear envelope. Part of nuclear pore outer ring. Implicated in nephrotic syndrome type 19. [provided by Alliance of Genome Resources, Jul 2025]

View all NUP160 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Loading comments…