rs55667289
This variant is located in the FLT4 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
vascular endothelial growth factor receptor 3 level
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.20
p 5.0e-19
N 47,745
Large GWAS
European
▶ClinVar annotation
Likely Benign★★★☆
10 submitters2 publicationsnot specified; not provided; Carcinoma of colon
View on ClinVar →About FLT4
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]
View all FLT4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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