rs558737289

This variant is located in the HDGFL3 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

1-linolenoyl-GPC (18:3) measurement

Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)

Allele A

OR 0.84

p 4.0e-8

N 14,296

Large GWAS

European

About HDGFL3

Predicted to enable microtubule binding activity. Predicted to be involved in microtubule polymerization; negative regulation of microtubule depolymerization; and neuron projection development. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all HDGFL3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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