rs559282550
This variant is located in the ANGPTL6 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
protein C-ets-2 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele A
OR 0.78
p 1.0e-59
N 10,708
Large GWAS
European
transmembrane protein 132C measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele A
OR 0.71
p 3.0e-48
N 10,708
Large GWAS
European
angiopoietin-related protein 1 measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele A
OR 0.58
p 3.0e-32
N 10,708
Large GWAS
European
▶ClinVar annotation
Benign★☆☆☆
1 submitterAbout ANGPTL6
Predicted to enable signaling receptor binding activity. Predicted to be involved in angiogenesis; blood coagulation; and cell differentiation. Located in collagen-containing extracellular matrix and extracellular exosome. Biomarker of gestational diabetes. [provided by Alliance of Genome Resources, Apr 2025]
View all ANGPTL6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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