rs55978915
This variant is located in the HCN2 gene.
▶ClinVar annotation
not specified; HCN2-related disorder; Thymoma; Malignant tumor of esophagus; Uveal melanoma; Sarcoma; Gastric cancer; Ovarian serous cystadenocarcinoma; Lung cancer; Cervical cancer; Uterine corpus endometrial carcinoma; Uterine carcinosarcoma; Acute myeloid leukemia
View on ClinVar →About HCN2
The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]
View all HCN2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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