rs559947349
This variant is located in the FOXO3B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of serine hydroxymethyltransferase, cytosolic in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.34
p 3.0e-20
N 47,745
Large GWAS
European
About FOXO3B
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in mitochondrial matrix. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all FOXO3B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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