rs56057809

This is a downstream gene variant variant in the FAM163B gene.

GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

smoking cessation

Saunders GRB et al. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 612(7941):720-724 (2022)
Allele T
OR 0.04
p 8.0e-85
N 1,400,535
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified

smoking status measurement

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.10
p 2.0e-11
N 202,070
Major Consortium StudyLarge GWAS
multi-ancestry

About FAM163B

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all FAM163B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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