rs562408
This is a intron variant variant in the SSBP3 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
P wave duration
Christophersen IE et al. “Fifteen Genetic Loci Associated With the Electrocardiographic P Wave.” Circulation. Cardiovascular Genetics 10(4) (2017)
Allele A
OR 0.53
p 2.0e-8
N 44,456
Large GWAS
multi-ancestry
TPE interval measurement
Ramírez J et al. “Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval.” American Journal of Human Genetics 106(6):764-778 (2020)
Allele A
OR 0.05
p 1.0e-10
N 71,338
Large GWAS
European
T wave morphology measurement
Ramírez J et al. “Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics.” Circulation. Arrhythmia and Electrophysiology 12(10):e007549 (2019)
Allele A
OR 0.03
p 4.0e-8
N 51,574
Large GWAS
European
About SSBP3
Predicted to enable single-stranded DNA binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all SSBP3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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