rs568039055

This variant is located in the ARL17A gene.

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

brain attribute

Sha Z et al. “The genetic architecture of structural left-right asymmetry of the human brain.” Nature Human Behaviour 5(9):1226-1239 (2021)
Allele C
OR —
p 8.0e-15
N 32,256
Large GWAS
European

forced expiratory volume

Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele G
OR 0.02
p 1.0e-13
N 373,397
Large GWAS
European

health trait

Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele G
OR 0.01
p 3.0e-11
N 405,979
Large GWAS
European

brain connectivity attribute

Sha Z et al. “Genetic architecture of the white matter connectome of the human brain.” Science Advances 9(7):eadd2870 (2023)
Allele G
OR 6.55
p 6.0e-11
N 30,810
Large GWAS
European

reaction time measurement

Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele G
OR 0.02
p 6.0e-15
N 404,449
Large GWAS
European

About ARL17A

Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all ARL17A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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