rs569475444

This variant is located in the GRID1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

grip strength measurement

Sarnowski C et al. “Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.” Plos One 16(7):e0253611 (2021)

Allele C

OR 8.09

p 9.0e-9

N 4,878

Large GWAS

multi-ancestry

About GRID1

This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]

View all GRID1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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