rs570639864

This variant is located in the WNT7B gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

heel bone mineral density

Morris JA et al. An atlas of genetic influences on osteoporosis in humans and mice. Nature Genetics 51(2):258-266 (2019)
Allele G
OR 0.14
p 1.0e-13
N 426,824
Large GWAS
European

About WNT7B

This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008]

View all WNT7B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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