rs57213254

This is a intron variant variant in the UBASH3B gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

inflammatory biomarker measurement, C-reactive protein measurement

Zhang R et al. “Genome-wide study of immune biomarkers in cerebrospinal fluid and serum from patients with bipolar disorder and controls.” Translational Psychiatry 10(1):58 (2020)

Allele T

OR 3.16

p 6.0e-9

N 291

Small GWAS

European

About UBASH3B

This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. [provided by RefSeq, Jul 2008]

View all UBASH3B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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