rs57284764

This is a regulatory region variant variant in the FMN1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

colorectal cancer

Tian J et al. “Developing an optimal stratification model for colorectal cancer screening and reducing racial disparities in multi-center population-based studies.” Genome Medicine 16(1):81 (2024)

Allele A

OR —

β 0.082

p 2.0e-12

N 839,703

Large GWAS

multi-ancestry

About FMN1

This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

View all FMN1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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