rs5743509

This variant is located in the BPI gene.

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ClinVar annotation

Benign★★★☆

2 submitters2 publications

not specified; not provided

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Research that mentions this SNP (1)

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Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy

AssociationN=1,711Savage DA et al.(2008)· Diabetologia

This case-control study investigated 1,111 non-synonymous SNPs in 1,711 type 1 diabetic individuals (894 cases with diabetic nephropathy, 817 controls) to assess genetic susceptibility to diabetic nephropathy. After correction for multiple testing, no SNPs demonstrated significant associations with diabetic nephropathy, including in subgroup analyses by ESRD status or diabetes duration.

Traits studied:Diabetic nephropathyEnd-stage renal disease (ESRD)

PubMed DOI Metascience Observatory

About BPI

This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has antimicrobial activity against gram-negative organisms. [provided by RefSeq, Nov 2014]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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