rs57455993
This variant is located in the UBE2U gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
amount of inactive tyrosine-protein kinase transmembrane receptor ROR1 (human) in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.18
p 5.0e-60
N 47,745
Large GWAS
European
About UBE2U
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein polyubiquitination. Predicted to be part of HULC complex. [provided by Alliance of Genome Resources, Jul 2025]
View all UBE2U variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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