rs5756415

This variant is located in the CSF2RB gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cytokine receptor common subunit beta measurement

Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)

Allele C

OR 0.72

p —

N 10,708

Large GWAS

European

oncostatin-M-specific receptor subunit beta measurement

Kuliesius J et al. “Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.” Communications Biology 8(1):1300 (2025)

Allele G

OR 0.87

p 5.0e-27

N 194

Small GWAS

European

About CSF2RB

The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]

View all CSF2RB variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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