rs5758466

This is a intron variant variant in the MEI1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

smoking cessation

Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)

Allele A

OR 0.01

p 1.0e-13

N 1,400,535

Large GWAS

European, East Asian, Hispanic or Latin American, African unspecified

About MEI1

Predicted to be involved in meiosis I. Predicted to act upstream of or within germ cell development; meiotic nuclear division; and meiotic spindle organization. Implicated in gestational trophoblastic neoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all MEI1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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