rs58074225
This is a upstream gene variant variant in the IQCH gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
smoking initiation
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele A
OR 0.01
p 2.0e-27
N 3,382,012
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
About IQCH
Predicted to act upstream of or within lncRNA transcription and single fertilization. Predicted to be active in nuclear speck. [provided by Alliance of Genome Resources, Jul 2025]
View all IQCH variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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