rs58415480
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Uterine leiomyoma
Sliz E et al. “Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata.” Nature Communications 14(1):542 (2023)
Allele C
OR 0.82
p 2.0e-81
N 367,903
Large GWAS
European
uterine fibroid
Rafnar T et al. “Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.” Nature Communications 9(1):3636 (2018)
Allele C
OR 1.18
p 9.0e-24
N 539,925
Large GWAS
European
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.20
p 7.0e-46
N 338,926
Large GWAS
multi-ancestry
Kim J et al. “Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups.” Nature Communications 16(1):2273 (2025)
Allele C
OR 0.18
p 2.0e-28
N 253,542
Meta-analysisLarge GWAS
East Asian, Central Asian, South Asian
Gallagher CS et al. “Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.” Nature Communications 10(1):4857 (2019)
Allele C
OR 0.17
p 2.0e-54
N 244,324
Large GWAS
European
Edwards TL et al. “A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.” Frontiers in Genetics 10:511 (2019)
Allele C
OR 1.19
p 2.0e-31
N 76,494
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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