rs58693904
This variant is located in the VPS8 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Takayasu arteritis
Ortiz-Fernández L et al. “Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study.” American Journal of Human Genetics 108(1):84-99 (2021)
Allele T
OR 1.51
p 4.0e-9
N 6,854
Large GWAS
multi-ancestry
About VPS8
Predicted to enable zinc ion binding activity. Involved in endosomal vesicle fusion. Located in early endosome. [provided by Alliance of Genome Resources, Jul 2025]
View all VPS8 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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