rs58711093
This is a intron variant variant in the IL1RAP gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
glucagon measurement
Meeks KAC et al. “Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits.” Genome Medicine 13(1):156 (2021)
Allele C
OR 0.65
p 3.0e-8
N 1,544
Large GWAS
multi-ancestry
About IL1RAP
This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]
View all IL1RAP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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