rs587738237

This variant is located in the RPRD2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

atopic eczema

Chen Y et al. “Genome-Wide Integration of Genetic and Genomic Studies of Atopic Dermatitis: Insights into Genetic Architecture and Pathogenesis.” The Journal of Investigative Dermatology 142(11):2958-2967.e8 (2022)

Allele T

OR 0.41

p 1.0e-9

N 837,496

Large GWAS

multi-ancestry

About RPRD2

Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in mRNA 3'-end processing. Part of transcription preinitiation complex. [provided by Alliance of Genome Resources, Jul 2025]

View all RPRD2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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